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February 2023

Luis Alberto Baena Lopez, Sir William Dunn School of Pathology
Paired identification of gene targets and pharmacological drugs with anti-oncogenic potential

Ejung Moon, Eileen Parkes, Claire Edwards, Department of Oncology, Nuffield Department of Surgical Sciences 
Characterisation of the role of MAFF in bone metastatic breast cancer

Matthew Bottomley, Elie Antoun, Graham Ogg, CAMS Oxford Institute, Nuffield Department of Medicine 
Single-cell spatial transcriptomic profiling to delineate changes in tumour-associated macrophage behaviour in cutaneous squamous cell carcinoma with immunosuppression

Grigore-Astride Gafencu, Calliope Dendrou, Anna Schuh, Department of Oncology, Oxford molecular Diagnostic Centre 
Comprehensive multi-modal assessment of peripheral blood from healthy elderly males: a key component in the interpretation of the data from the pilot collaboration between OXPLORED and CARTOGRAPHY

Nikolaos Kanellakis, Najib Rahman, Tao Dong, China Oxford Institute, Nuffield Department of Medicine 
Phenotype and characterisation of the immunosuppressive mechanisms of malignant pleural effusion

Adam Cribbs, Jianfeng Sun, Udo Oppermann, Tim Elliott, NDORMS, Botnar Research Institute
Single-cell spliceosome map establishment of immune cells

Jane McKeating, Alberto Quaglia, Ellie Barnes, Emma Culber, Fadi Issa, Tim Elliott, Adrian Harris, Stephanie Roessler, Nuffield Department of Medicine, University College London Cancer Institute, OUH Hospital NHS Trust, Oxford, Translational Gastroenterology Unit, Oxford Radcliffe NHS Trust, Nuffield Department of Surgery, Centre for Immuno-oncology, Department of Oncology & University of Heidelberg
Targeting the acidic microenvironment in hepatocellular carcinoma to overcome resistance to immunotherapy

Carol Leung, Ricardo Fernandes, Ludwig Institute 
Developing T-cell engager bispecific antibodies targeting the Epstein-Barr virus latent membrane proteins

Chung Ying Chan, Eileen Parkes, Richard Bryant, Su Phyu, Kel Tan, Department of Oncology
Stratifying treatment for MYC amplified prostate cancer

Simei Go, Eric O'Neil, Keaton Jones, Berna Bou Tayeh, Department of Oncology, Nuffield Department of Surgical Science, Ludwig Cancer Research 
Infiltrating NK cells as immunoregulators in pancreatic cancer?

Oni Chowdhury, Adam Mead, Weatherall Institute of Molecular Medicine
Applying single cell genomics to clinical diagnostics - detection of TP53 mutant clones and collaborating genetic aberrations in myeloid neoplasms

Gemma Hancock, Ricardo Ferreira, Wellcome Trust, Nuffield Department of Women's & Reproductive Health
Deep phenotyping of CD4+ T-cells in high-risk human papillomavirus (hrHPV) infection

Eleni Adamopoulou, Isabela Pedroza-Pacheco, Kerry Fisher, Marco Fritzsche, Eileen Parkes, Nicola Ternette, Nuffield Department of Medicine 
Immune-profiling of malignant ascites from ovarian cancer patients as a route to sampling the tumour microenvironment

Margarida Rei, Xin Lu, Ricado Fernandes, Ruichong Ma, Ludwig Cancer Research
Discovery of T cell antigen targets in glioblastoma

Valentine Macaulay, Fadi Issa, Eric O'Neill, Nuffield Department of Surgical Sciences
Investigating immunosuppressive effects of IGF-1 as a growth factor for regulatory T-cells in prostate cancer

George Adigbli, Oliver Cassell, Janna Hester, Fadi Issa, Miranda Payne, Olivia Espinosa, Nuffield Department of Surgical Sciences
Early Risk Stratification by Lymph Liquid Biopsy In Melanoma