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February 2021

Tom Agnew, Sir William Dunn School of Pathology
ARH3 as a potential new biomarker in breast, ovarian and pancreatic and prostate cancer

Elizabeth Mann et al., The Kennedy Institute of Rheumatology, NDORMS
Ex vivo phenotyping of Th17 cells from colorectal cancer patients

Kourosh Honarmand Ebrahimi & James McCullagh, Department of Chemistry, Chemistry Research Laboratory
Metabolomics investigation of an emerging immunometabolic pathway linking viral infection and inflammation to cancer

Linna Zhou, The Ludwig Institute & Department of Chemistry
Engineered gastrointestinal tissues to investigate the influence of enteric neurons in cancer progression

Mariolina Salio & Graham Collins, Human Immunology Unit & Department of Haematology, Oxford University Hospitals
Immune microenvironment signatures predictive of response in patients with classical Hodgkin Lymphoma treated with checkpoint inhibitors

Karthik Ramasamy & Ross Sadler, Department of Haematology, Oxford University Hospitals & Nuffield Department of Medicine
Post translational modification of free light chains as a biomarker for progression from monoclonal gammopathy of undetermined significance to myeloma

Monica Olcina et al., MRC Oxford Institute for Radiation Oncology, Department of Oncology
C5aR1 as a biomarker in ovarian cancer – Towards the development of radioligands for imaging and therapy of C5aR1 expressing tumours

Ricardo Fernandes, Nuffield Department of Medicine
Development of a new approach to target FLT3 signalling in AML

Simon Carr & Wojciech Barczak, Department of Oncology
Tumour specific neo-antigens derived from the non-coding genome

Andrew Blackford, Department of Oncology
Characterising short linear peptide motifs in tumour suppressor proteins

Thomas Lanyon-Hogg, Department of Pharmacology
Development of novel Hedgehog acyltransferase inhibitors from HTS hits to lead series

Val Macaulay, Ian Mills & Jack Mills, Department of Oncology & Nuffield Department of Surgical Sciences
Investigating nuclear IGF-1R function in clinical prostate cancers

Wayne Paes et al., Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine
Empirical determination of molecular biomarkers for precision-based immunotherapy in colorectal cancer

Shijie Cai et al., Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine
Identification of small molecule inhibitors and synthetic lethality for GTP cyclohydrolase in triple-negative breast cancer