January 2017
Dr John Jacob, Clinical Neuroscience
Dr Vincenzo D’Angiolella, Dr Frances Willenbrock, Oncology
Resolving the significance and mechanism of altered cholesterol metabolism in sonic hedgehog driven medulloblastoma
Prof Catherine Green, WTCHG
SetD3 as a novel target for cancer therapeutics
Prof Alison Banham, NDCLS
Dr Daniel Ebner, TDI
CRISPR Whole Genome Screen to Identify Pathways Driving Expression of the FOXP1 Oncogene
Dr Jia-Ling Ruan, Prof Anne Kiltie, Oncology
Immunomodulation by Gemcitabine-Based Chemoradiation Therapy in Muscle Invasive Bladder Cancer
Prof Simon Leedham, WTCHG
Using somatic mutation to reflect variable underlying disease pathogenesis in colorectal cancer
Dr Imre Mäger, DPAG
The proteome and brain microvascular endothelial cell interactions of brain-metastatic breast cancer extracellular vesicles
Prof Shona Murphy, Dr Justyna Zaborowska, Dunn School
CDK12 at the front line of the DNA Damage Response
Dr Bart Cornelissen, Oncology
Discovery of novel targets to image the effects of irradiation
Dr Gillian Farnie, NDORMS
Prof Claire Edwards, NDS
The influence of bone marrow adipocytes on the activity and dormancy of breast cancer metastasis
Dr Jurgen Brem, Chemistry
Dynamic combinatoria chemistry to develop novel anticancer agents
Prof Panagis Filippakopoulos, SGC
Prof Eric O’Neil, Oncology
Prof Tom Milne, Wimm
BRD4-directed recruitment of NuRD as a potential therapeutic target in cancer
Dr Johanna Michl, Prof Madalena Tarsounas, Oncology
Developing inhibitors of the Fanconi anemia pathway for the treatment of BRCA1/2-deficient cancers
Prof Adam Mead, WIMM
Measuring DNA Damage in Single Cells Using a Novel High Throughput Genomic Assay
Dr Nick Coupe, Oncology
In Vivo investigation of the orphan receptor ROR2 in angiogenesis and bevacizumab sensitivity in BRAF mutant melanoma
Dr Alfredo Castello Palomares, Biochemistry
Decoding the role of the RNA binding activity of p53
Prof Ian Tomlinson, Dr Lennard Lee, WTCHG
Colorectal cancer metastasis signatures and immune profiling of the lymphoid niche – predicting tumour recurrence
Dr Nicola Farrer, Chemistry
Ultrasonic Delivery of Pt(IV) Prodrugs
Dr Annabelle Lewis, Dr Roland Arnold, WTCHG
Identification of drivers of colon cancer cell differentiation: using a validated genomewide CRISPR transcriptional activation screen.
Dr Yanyan Jiang, Dr Anderson Ryan, Oncology
Targeting DNA-PK to selectively potentiate radiosensitivity in a xenograft model of lung cancer by contextual synthetic lethality
Dr Bilyana Stoilova, Prof Paresh Vyas, MHU
Determining the heterogeneity of progenitor phenotypes in human Acute Myeloid Leukaemia
Prof Nicholas La Thangue, Dr Rebecca Miller, Oncology
Dr Weston Struwe, Glycobiology
Heparin sulfate oligosaccharides that bind and inhibit tumourigenic growth have potential as drugs to limit glioma progression
Dr Anjali Kusumbe, Kennedy
Regulation of breast cancer cell metastasis by distinct blood vessel subtypes in the bone marrow microenvironment
Dr Tom McAllister, Dr Akane Kawamura, Chemistry
Cyclic Peptides inhibitors of the IGF/IGF-1R Interaction
Prof Ahmed Ahmed, NDOG
Targeting FER for the treatment of ovarian cancer